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NIFD_3_S_0005_MR_t1_mprage_ND_br_raw_20160518200000281_123_S442841_I709843

On a T1-weighted brain MRI of a 63-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe, more pronounced on the left - atrophies of frontal lobe on gyrus rectus (mild), triangular inf. frontal gyrus (mild) and medial frontal cortex (mild) - mild focal atrophy of temporal lobe on planum temporale - mild focal atrophy of occipital lobe on lingual gyrus - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0339_MR_T1_mprage_S3_DIS3D_br_raw_20170629002457144_144_S577807_I867541

On a T1-weighted brain MRI of a 63-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: temporal pole (severe), inf. temporal gyrus (moderate), middle temporal gyrus (mild), fusiform gyrus (moderate) and sup. temporal gyrus (mild) - moderate bilateral atrophy of the insular cortex, more pronounced on the right, with focal volume reduction observed in the following subregions: anterior insula (mild) and central operculum (mild) - moderate atrophy of the limbic cortex, more pronounced on the right, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (moderate) and entorhinal area (mild) - atrophies of frontal lobe on medial frontal cortex (mild), medial orbital gyrus (mild) and gyrus rectus (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the right - severe bilateral atrophy of the hippocampus, more pronounced on the right - moderate bilateral atrophy of the accumbens, more pronounced on the right - no evidence of atrophy in the basal forebrain - mild right atrophy of the putamen - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_2_S_0027_MR_MT1__GradWarp__N3m_Br_20130103113648528_S177998_I353170

On a T1-weighted brain MRI of a 58-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the temporal lobe, with focal volume reduction observed in the following subregions: temporal pole (severe), fusiform gyrus (mild) and middle temporal gyrus (mild) - mild bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: entorhinal area (moderate) and parahippocampal gyrus (moderate) - mild atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (moderate) - mild focal atrophy of frontal lobe on lateral orbital gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the hippocampus, more pronounced on the left - severe bilateral atrophy of the amygdala - mild bilateral atrophy of the putamen - mild atrophy of the accumbens, more pronounced on the right - mild atrophy of the pallidum - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0085_MR_T1_mprage_S3_DIS3D_br_raw_20120307000133150_31_S143023_I288641

On a T1-weighted brain MRI of a 47-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: middle frontal gyrus (moderate) - moderate focal atrophy of temporal lobe on temporal pole - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate atrophy of the thalamus, more pronounced on the left - moderate bilateral atrophy of the hippocampus - mild atrophy of the caudate, more pronounced on the left - mild left atrophy of the pallidum - mild left atrophy of the ventral dc - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - severe enlargement of the external csf - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0024_MR_t1_mprage_S7_DIS3D_br_raw_20110203091851798_6_S98780_I215642

On a T1-weighted brain MRI of a 67-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on anterior orbital gyrus (mild) and middle frontal gyrus (mild) - mild focal atrophy of temporal lobe on temporal pole - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the ventral dc - mild left atrophy of the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0289_MR_t1_mprage__br_raw_20170628140008007_55_S576470_I865828

On a T1-weighted brain MRI of a 60-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on sup. temporal gyrus - moderate focal atrophy of limbic cortex on anterior cingulate gyrus - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0255_MR_MPRAGE_S2_DIS3D__br_raw_20160902183019481_26_S496086_I772309

On a T1-weighted brain MRI of a 60-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of occipital lobe on inf. occipital gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0260_MR_t1_mprage__br_raw_20160902193301261_114_S496198_I772429

On a T1-weighted brain MRI of a 68-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: parietal operculum (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0044_MR_t1_mprage_S3_DIS3D_br_raw_20110525094555007_3_S109914_I237292

On a T1-weighted brain MRI of a 80-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the occipital lobe, with focal volume reduction observed in the following subregions: calcarine cortex (moderate) and lingual gyrus (moderate) - mild focal atrophy of frontal lobe on precentral gyrus medial segment - mild focal atrophy of temporal lobe on middle temporal gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0176_MR_T1_mprage_S3_DIS3D_br_raw_20140831170526452_55_S228978_I441286

On a T1-weighted brain MRI of a 53-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on subcallosal area - mild focal atrophy of limbic cortex on anterior cingulate gyrus - mild focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - mild right atrophy of the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0212_MR_T1_mprage_S3_DIS3D_br_raw_20170817105545257_129_S597537_I890918

On a T1-weighted brain MRI of a 53-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0282_MR_t1_mprage__br_raw_20160903205123186_157_S496728_I773037

On a T1-weighted brain MRI of a 73-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on precentral gyrus (moderate) and middle frontal gyrus (mild) - mild focal atrophy of temporal lobe on transverse temporal gyrus - mild focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0246_MR_t1_mprage__br_raw_20160902161114592_62_S495911_I772101

On a T1-weighted brain MRI of a 73-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on precentral gyrus medial segment (mild), gyrus rectus (mild) and middle frontal gyrus (mild) - mild focal atrophy of insular cortex on posterior insula - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - mild bilateral atrophy of the putamen - mild atrophy of the accumbens - mild atrophy of the pallidum - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

NIFD_1_S_0009_MR_t1_mprage_S3_DIS3D_br_raw_20110203200504338_149_S98892_I215776

On a T1-weighted brain MRI of a 67-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: temporal pole (severe), fusiform gyrus (moderate), inf. temporal gyrus (moderate) and middle temporal gyrus (mild) - mild atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (moderate) and posterior insula (moderate) - mild focal atrophy of occipital lobe on calcarine cortex - atrophies of limbic cortex on entorhinal area (mild) and parahippocampal gyrus (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the right - severe bilateral atrophy of the accumbens, more pronounced on the right - moderate bilateral atrophy of the hippocampus, more pronounced on the right - moderate bilateral atrophy of the pallidum, more pronounced on the right - no evidence of atrophy in the basal forebrain - mild atrophy of the putamen, more pronounced on the right - mild atrophy of the caudate, more pronounced on the right - mild atrophy of the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - mild bilateral enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0056_MR_t1_mprage_S3_DIS3D_br_raw_20111019194910586_85_S125860_I261681

On a T1-weighted brain MRI of a 59-year-old male subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: precuneus (mild) and supramarginal gyrus (mild) - atrophies of frontal lobe on sup. frontal gyrus (moderate), posterior orbital gyrus (mild) and gyrus rectus (mild) - mild focal atrophy of temporal lobe on planum polare - mild focal atrophy of limbic cortex on anterior cingulate gyrus - mild focal atrophy of insular cortex on parietal operculum - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the thalamus, more pronounced on the left - mild atrophy of the caudate, more pronounced on the left - mild bilateral atrophy of the accumbens - mild bilateral atrophy of the amygdala - mild bilateral atrophy of the pallidum - mild atrophy of the hippocampus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the lateral ventricle - mild left enlargement of the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0328_MR_T1_mprage_S16_DIS3D__br_raw_20170817112235493_146_S597656_I891084

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: precentral gyrus (severe), opercular inf. frontal gyrus (mild), triangular inf. frontal gyrus (mild) and sup. frontal gyrus medial segment (mild) - mild bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: sup. parietal lobule (mild) and supramarginal gyrus (mild) - mild atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: central operculum (mild), anterior insula (mild) and frontal operculum (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the putamen, more pronounced on the left - moderate bilateral atrophy of the pallidum, more pronounced on the left - mild bilateral atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild right enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the 3rd ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0331_MR_t1_mprage__br_raw_20170628193041306_42_S577186_I866720

On a T1-weighted brain MRI of a 64-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: opercular inf. frontal gyrus (moderate) and sup. frontal gyrus (mild) - mild atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: frontal operculum (mild) - mild focal atrophy of occipital lobe on inf. occipital gyrus - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe For the subcortical structures: - severe bilateral atrophy of the caudate, more pronounced on the left - moderate bilateral atrophy of the putamen, more pronounced on the left - mild left atrophy of the thalamus - mild left atrophy of the pallidum - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_3_S_0001_MR_t1_mprage_S3_DIS3D_br_raw_20160516150232756_71_S441705_I708484

On a T1-weighted brain MRI of a 58-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on orbital inf. frontal gyrus (mild) and triangular inf. frontal gyrus (mild) - atrophies of limbic cortex on posterior cingulate gyrus (mild) and middle cingulate gyrus (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the amygdala - mild bilateral atrophy of the hippocampus - no evidence of atrophy in the basal forebrain - mild left atrophy of the putamen - mild left atrophy of the pallidum - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the caudate - no evidence of atrophy in the thalamus For the ventricles: - severe bilateral enlargement of the lateral ventricle - mild right enlargement of the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_3_S_0011_MR_T1_mprage_ND_S3_DIS3D__br_raw_20160519104824325_34_S443835_I710941

On a T1-weighted brain MRI of a 65-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: entorhinal area (moderate), parahippocampal gyrus (mild) and middle cingulate gyrus (mild) - severe atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (severe), inf. temporal gyrus (moderate), planum polare (mild), middle temporal gyrus (mild) and sup. temporal gyrus (mild) - atrophies of insular cortex on posterior insula (mild) and central operculum (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - mild atrophy of the accumbens, more pronounced on the left - moderate left atrophy of the hippocampus - mild left atrophy of the caudate - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle, more pronounced on the left - mild enlargement of the lateral ventricle, more pronounced on the left - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0066_MR_t1_mprage_S3_DIS3D_br_raw_20111209095320061_124_S132307_I270740

On a T1-weighted brain MRI of a 62-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of occipital lobe on middle occipital gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the caudate - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0162_MR_T1_mprage_S3_DIS3D_br_raw_20140701124018436_69_S223836_I433911

On a T1-weighted brain MRI of a 67-year-old male subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the basal forebrain - mild atrophy of the ventral dc - mild atrophy of the pallidum - no evidence of atrophy in the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0202_MR_T1_mprage_S3_DIS3D_br_raw_20170817131148687_130_S597998_I891534

On a T1-weighted brain MRI of a 54-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on medial orbital gyrus (moderate), gyrus rectus (moderate) and medial frontal cortex (moderate) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

NIFD_1_S_0307_MR_t1_mprage__br_raw_20160907144800490_96_S497652_I774130

On a T1-weighted brain MRI of a 62-year-old male subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on orbital inf. frontal gyrus (mild) and posterior orbital gyrus (mild) - atrophies of occipital lobe on inf. occipital gyrus (mild) and sup. occipital gyrus (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the thalamus - mild atrophy of the accumbens - mild left atrophy of the hippocampus - mild right atrophy of the putamen - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - moderate enlargement of the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0309_MR_t1_mprage__br_raw_20160909134218398_83_S497944_I774495

On a T1-weighted brain MRI of a 67-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of occipital lobe on inf. occipital gyrus - mild focal atrophy of limbic cortex on middle cingulate gyrus - mild focal atrophy of insular cortex on anterior insula - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_021_S_4254_MR_Accelerated_Sag_IR-SPGR__br_raw_20110926165228810_88_S123443_I258068

On a T1-weighted brain MRI of a 86-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the accumbens - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - mild right atrophy of the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_003_S_5187_MR_Accelerated_SAG_IR-SPGR__br_raw_20130610202342271_157_S191910_I375951

On a T1-weighted brain MRI of a 62-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on planum temporale - mild focal atrophy of parietal lobe on precuneus - atrophies of occipital lobe on calcarine cortex (mild), occipital fusiform gyrus (mild), sup. occipital gyrus (mild) and occipital pole (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the hippocampus - moderate bilateral atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild right enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_135_S_4446_MR_MPRAGE_br_raw_20120117112205836_47_S136801_I278378

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the frontal lobe, with focal volume reduction observed in the following subregions: middle frontal gyrus (moderate) and frontal pole (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_011_S_4105_MR_MPRAGE_br_raw_20110719125904723_114_S115213_I245491

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on gyrus rectus (moderate) and sup. frontal gyrus medial segment (mild) - mild focal atrophy of temporal lobe on fusiform gyrus - mild focal atrophy of parietal lobe on supramarginal gyrus - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild bilateral enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_131_S_5138_MR_MPRAGE_br_raw_20130417113829938_29_S187196_I367565

On a T1-weighted brain MRI of a 61-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on medial orbital gyrus - atrophies of temporal lobe on sup. temporal gyrus (mild) and transverse temporal gyrus (mild) - mild focal atrophy of parietal lobe on sup. parietal lobule - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the pallidum - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_032_S_4348_MR_MPRAGE_br_raw_20111118112458497_150_S130131_I267561

On a T1-weighted brain MRI of a 67-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the frontal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: middle frontal gyrus (severe) and subcallosal area (mild) - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: postcentral gyrus (mild) - mild atrophy of the occipital lobe, with focal volume reduction observed in the following subregions: sup. occipital gyrus (mild) - mild focal atrophy of temporal lobe on fusiform gyrus - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the pallidum - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

ADNI_003_S_4900_MR_Accelerated_SAG_IR-SPGR__br_raw_20130702111838357_9_S162272_I325733

On a T1-weighted brain MRI of a 60-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_136_S_4727_MR_MPRAGE_br_raw_20120606151218245_114_S153015_I308415

On a T1-weighted brain MRI of a 74-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on triangular inf. frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_126_S_4494_MR_Accelerated_Sag_IR-SPGR__br_raw_20120131123025629_91_S138966_I281601

On a T1-weighted brain MRI of a 71-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on posterior orbital gyrus - mild focal atrophy of limbic cortex on entorhinal area - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the amygdala - mild bilateral atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild right enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_011_S_4120_MR_MPRAGE_br_raw_20110715111757104_135_S114811_I244900

On a T1-weighted brain MRI of a 82-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) - mild focal atrophy of frontal lobe on supplementary motor cortex - atrophies of temporal lobe on inf. temporal gyrus (mild), transverse temporal gyrus (mild) and temporal pole (mild) - moderate focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - mild right atrophy of the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_007_S_5196_MR_Accelerated_SAG_IR-SPGR__br_raw_20130612130338802_16_S192134_I376238

On a T1-weighted brain MRI of a 73-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on medial frontal cortex - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the amygdala - moderate bilateral atrophy of the hippocampus - mild atrophy of the ventral dc - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

AD

ADNI_024_S_4084_MR_MPRAGE_br_raw_20110620162005802_83_S112129_I241013

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on anterior orbital gyrus - mild focal atrophy of occipital lobe on sup. occipital gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the putamen - no evidence of atrophy in the amygdala - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_007_S_4488_MR_Accelerated_SAG_IR-SPGR__br_raw_20120131104026380_93_S138944_I281559

On a T1-weighted brain MRI of a 73-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of parietal lobe on sup. parietal lobule - mild focal atrophy of limbic cortex on middle cingulate gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_011_S_4827_MR_MPRAGE_br_raw_20120703085506250_153_S156389_I314042

On a T1-weighted brain MRI of a 72-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: postcentral gyrus medial segment (mild) - mild focal atrophy of frontal lobe on opercular inf. frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate atrophy of the amygdala, more pronounced on the left - mild left atrophy of the hippocampus - mild left atrophy of the putamen - mild left atrophy of the thalamus - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - severe enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_094_S_4503_MR_Accelerated_SAG_IR-SPGR__br_raw_20120229095213816_59_S141558_I286228

On a T1-weighted brain MRI of a 72-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of occipital lobe on middle occipital gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_137_S_4587_MR_MPRAGE_br_raw_20120416110004702_57_S147267_I297501

On a T1-weighted brain MRI of a 66-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on sup. frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the hippocampus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_002_S_4264_MR_MPRAGE_br_raw_20111006131112761_140_S124589_I259796

On a T1-weighted brain MRI of a 75-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on planum polare - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - severe bilateral atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild left enlargement of the inf. lateral ventricle - mild left enlargement of the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_037_S_4028_MR_MPRAGE_br_raw_20110425125155063_168_S105075_I228854

On a T1-weighted brain MRI of a 64-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the insular cortex, with focal volume reduction observed in the following subregions: parietal operculum (severe) - mild focal atrophy of frontal lobe on middle frontal gyrus - mild focal atrophy of occipital lobe on middle occipital gyrus - mild focal atrophy of limbic cortex on middle cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe For the subcortical structures: - mild left atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_099_S_4124_MR_MPRAGE_br_raw_20110728114051898_41_S116633_I247513

On a T1-weighted brain MRI of a 73-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the limbic cortex - mild focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the hippocampus, more pronounced on the left - mild bilateral atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_094_S_4560_MR_Accelerated_SAG_IR-SPGR__br_raw_20120326195612702_23_S144258_I291214

On a T1-weighted brain MRI of a 70-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of occipital lobe on calcarine cortex - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

ADNI_016_S_5057_MR_Accelerated_SAG_IR-SPGR__br_raw_20130226082518326_195_S183095_I361230

On a T1-weighted brain MRI of a 75-year-old male subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_010_S_5163_MR_MPRAGE_br_raw_20130606120905404_67_S191475_I375336

On a T1-weighted brain MRI of a 67-year-old male subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the frontal lobe, with focal volume reduction observed in the following subregions: middle frontal gyrus (moderate), medial orbital gyrus (moderate), gyrus rectus (mild) and opercular inf. frontal gyrus (mild) - mild focal atrophy of temporal lobe on inf. temporal gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the external csf - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_135_S_4676_MR_MPRAGE_br_raw_20120419112023754_126_S147672_I298456

On a T1-weighted brain MRI of a 79-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of insular cortex on anterior insula - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - mild atrophy of the hippocampus, more pronounced on the right - mild right atrophy of the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

AD

ADNI_135_S_5275_MR_MPRAGE_br_raw_20130805125009417_8_S197268_I384344

On a T1-weighted brain MRI of a 78-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on sup. frontal gyrus medial segment - atrophies of temporal lobe on planum polare (mild) and sup. temporal gyrus (mild) - mild focal atrophy of parietal lobe on angular gyrus - atrophies of occipital lobe on cuneus (mild) and occipital fusiform gyrus (mild) - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the putamen - mild bilateral atrophy of the pallidum - mild bilateral atrophy of the ventral dc - mild atrophy of the caudate - mild right atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the thalamus For the ventricles: - mild right enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_135_S_4863_MR_MPRAGE_br_raw_20120801122802329_55_S159175_I320487

On a T1-weighted brain MRI of a 71-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on inf. temporal gyrus - mild focal atrophy of parietal lobe on postcentral gyrus medial segment - mild focal atrophy of occipital lobe on lingual gyrus - mild focal atrophy of limbic cortex on entorhinal area - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_024_S_4158_MR_MPRAGE_br_raw_20110815114120024_16_S118583_I250350

On a T1-weighted brain MRI of a 85-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of limbic cortex on parahippocampal gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the ventral dc - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_073_S_4739_MR_MPRAGE_br_raw_20120516150253805_135_S150755_I304867

On a T1-weighted brain MRI of a 66-year-old male subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: angular gyrus (mild) - mild atrophy of the occipital lobe, with focal volume reduction observed in the following subregions: cuneus (mild) - mild focal atrophy of frontal lobe on precentral gyrus - atrophies of temporal lobe on temporal pole (mild) and middle temporal gyrus (mild) - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild right atrophy of the accumbens - mild left atrophy of the thalamus - mild left atrophy of the caudate - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

ADNI_003_S_4119_MR_Accelerated_SAG_IR-SPGR__br_raw_20110816161703653_34_S118980_I250900

On a T1-weighted brain MRI of a 79-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on precentral gyrus medial segment - atrophies of occipital lobe on inf. occipital gyrus (mild) and sup. occipital gyrus (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_007_S_4568_MR_Accelerated_SAG_IR-SPGR__br_raw_20120301171636342_136_S142282_I287481

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: sup. parietal lobule (moderate) - mild focal atrophy of occipital lobe on occipital pole - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the amygdala - no evidence of atrophy in the basal forebrain - mild atrophy of the accumbens - mild atrophy of the caudate - mild atrophy of the hippocampus - mild atrophy of the ventral dc - mild right atrophy of the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_041_S_4427_MR_MPRAGE_br_raw_20111219161558046_114_S133927_I273198

On a T1-weighted brain MRI of a 72-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of limbic cortex on posterior cingulate gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

ADNI_014_S_4039_MR_MPRAGE_br_raw_20110603075656539_127_S110533_I238745

On a T1-weighted brain MRI of a 56-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: precuneus (severe) and angular gyrus (mild) - mild atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: sup. temporal gyrus (mild), fusiform gyrus (mild) and middle temporal gyrus (mild) - mild focal atrophy of frontal lobe on anterior orbital gyrus - mild focal atrophy of occipital lobe on occipital fusiform gyrus - moderate focal atrophy of insular cortex on central operculum - no evidence of atrophy in the limbic cortex For the subcortical structures: - moderate atrophy of the amygdala, more pronounced on the right - mild bilateral atrophy of the accumbens, more pronounced on the right - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the inf. lateral ventricle - mild right enlargement of the lateral ventricle - severe enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_011_S_4912_MR_MPRAGE_br_raw_20120823092531324_144_S162366_I325980

On a T1-weighted brain MRI of a 70-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on orbital inf. frontal gyrus - mild focal atrophy of parietal lobe on supramarginal gyrus - mild focal atrophy of limbic cortex on parahippocampal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the hippocampus, more pronounced on the left - mild bilateral atrophy of the caudate - mild atrophy of the amygdala - no evidence of atrophy in the basal forebrain - mild atrophy of the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_127_S_5028_MR_Accelerated_Sag_IR-SPGR__br_raw_20121114162609124_113_S174622_I346691

On a T1-weighted brain MRI of a 62-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on middle frontal gyrus - mild focal atrophy of temporal lobe on inf. temporal gyrus - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

NIFD_2_S_0004_MR_MT1__GradWarp__N3m_Br_20120105162046732_S133219_I275501

On a T1-weighted brain MRI of a 66-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, with focal volume reduction observed in the following subregions: temporal pole (severe), inf. temporal gyrus (severe), fusiform gyrus (mild), planum polare (mild) and middle temporal gyrus (mild) - severe bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: parahippocampal gyrus (severe), entorhinal area (severe), anterior cingulate gyrus (moderate) and middle cingulate gyrus (mild) - severe bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (severe), posterior insula (moderate) and frontal operculum (mild) - mild bilateral atrophy of the frontal lobe, with focal volume reduction observed in the following subregions: gyrus rectus (severe), medial frontal cortex (moderate), medial orbital gyrus (moderate), middle frontal gyrus (mild) and subcallosal area (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - severe bilateral atrophy of the accumbens - severe bilateral atrophy of the hippocampus - severe bilateral atrophy of the putamen - mild bilateral atrophy of the pallidum - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - moderate bilateral enlargement of the lateral ventricle - moderate enlargement of the external csf - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0007_MR_t1_mprage_S3_DIS3D_br_raw_20110203131001772_58_S98863_I215741

On a T1-weighted brain MRI of a 50-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: temporal pole (severe), middle temporal gyrus (severe), fusiform gyrus (moderate), inf. temporal gyrus (moderate), planum polare (mild) and sup. temporal gyrus (mild) - severe bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: parahippocampal gyrus (moderate), entorhinal area (moderate) and anterior cingulate gyrus (mild) - atrophies of insular cortex on anterior insula (moderate) and posterior insula (moderate) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the putamen, more pronounced on the right - severe bilateral atrophy of the amygdala, more pronounced on the right - severe bilateral atrophy of the accumbens, more pronounced on the right - severe bilateral atrophy of the hippocampus, more pronounced on the right - moderate bilateral atrophy of the caudate, more pronounced on the right - no evidence of atrophy in the basal forebrain - mild right atrophy of the pallidum - no evidence of atrophy in the ventral dc - no evidence of atrophy in the thalamus For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - severe enlargement of the external csf - moderate enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: middle frontal gyrus (severe), gyrus rectus (severe), triangular inf. frontal gyrus (severe), frontal pole (moderate), medial frontal cortex (moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (moderate), opercular inf. frontal gyrus (mild), lateral orbital gyrus (mild), medial orbital gyrus (mild) and sup. frontal gyrus medial segment (mild) - severe bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (severe) and middle cingulate gyrus (mild) - severe bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (severe), parietal operculum (mild) and frontal operculum (mild) - mild atrophy of the parietal lobe, more pronounced on the left - mild focal atrophy of temporal lobe on sup. temporal gyrus - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the thalamus, more pronounced on the left - severe bilateral atrophy of the accumbens, more pronounced on the left - moderate bilateral atrophy of the putamen, more pronounced on the left - moderate bilateral atrophy of the pallidum, more pronounced on the left - moderate bilateral atrophy of the amygdala - mild bilateral atrophy of the ventral dc - mild atrophy of the hippocampus - no evidence of atrophy in the basal forebrain For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - moderate bilateral enlargement of the lateral ventricle - severe enlargement of the external csf - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0012_MR_t1_mprage_S3_DIS3D_br_raw_20110203110049942_46_S98799_I215664

On a T1-weighted brain MRI of a 71-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: middle frontal gyrus (severe), medial orbital gyrus (severe), gyrus rectus (moderate), sup. frontal gyrus medial segment (moderate), medial frontal cortex (moderate), lateral orbital gyrus (mild), precentral gyrus medial segment (mild), subcallosal area (mild), sup. frontal gyrus (mild), orbital inf. frontal gyrus (mild), anterior orbital gyrus (mild), posterior orbital gyrus (mild), precentral gyrus (mild), supplementary motor cortex (mild) and opercular inf. frontal gyrus (mild) - severe bilateral atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior insula (severe), central operculum (severe), posterior insula (moderate), frontal operculum (moderate) and parietal operculum (mild) - severe bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (mild), entorhinal area (mild) and parahippocampal gyrus (mild) - mild atrophy of the parietal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: supramarginal gyrus (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the accumbens, more pronounced on the left - severe bilateral atrophy of the amygdala, more pronounced on the left - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the putamen, more pronounced on the left - no evidence of atrophy in the basal forebrain - mild left atrophy of the thalamus - mild left atrophy of the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - moderate bilateral enlargement of the inf. lateral ventricle - mild left enlargement of the lateral ventricle - severe enlargement of the external csf - moderate enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0097_MR_T1_mprage_S3_DIS3D_br_raw_20120819171037400_152_S161488_I324741

On a T1-weighted brain MRI of a 69-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: temporal pole (severe), fusiform gyrus (severe), inf. temporal gyrus (severe), middle temporal gyrus (severe) and sup. temporal gyrus (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (moderate) - mild focal atrophy of frontal lobe on subcallosal area - moderate focal atrophy of insular cortex on posterior insula - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the right - severe bilateral atrophy of the accumbens, more pronounced on the right - moderate bilateral atrophy of the hippocampus, more pronounced on the right - no evidence of atrophy in the basal forebrain - mild right atrophy of the caudate - mild right atrophy of the putamen - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0072_MR_T1_mprage_S3_DIS3D_br_raw_20170816175300325_153_S597008_I890174

On a T1-weighted brain MRI of a 69-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (severe), middle temporal gyrus (severe), inf. temporal gyrus (severe), fusiform gyrus (moderate), planum temporale (mild) and sup. temporal gyrus (mild) - moderate atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior insula (moderate), posterior insula (mild) and parietal operculum (mild) - moderate focal atrophy of frontal lobe on posterior orbital gyrus - atrophies of limbic cortex on entorhinal area (severe) and parahippocampal gyrus (severe) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - severe bilateral atrophy of the hippocampus, more pronounced on the left - moderate bilateral atrophy of the accumbens, more pronounced on the left - mild atrophy of the putamen, more pronounced on the left - no evidence of atrophy in the basal forebrain - mild left atrophy of the pallidum - mild left atrophy of the thalamus - no evidence of atrophy in the caudate - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle, more pronounced on the left - no evidence of enlargements in the lateral ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0130_MR_T1_mprage_S3_DIS3D_br_raw_20130719163246403_84_S195891_I381770

On a T1-weighted brain MRI of a 58-year-old male subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) - mild atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (moderate) - mild focal atrophy of frontal lobe on middle frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - moderate bilateral atrophy of the caudate, more pronounced on the left - moderate bilateral atrophy of the putamen, more pronounced on the left - mild atrophy of the pallidum, more pronounced on the left - mild atrophy of the thalamus, more pronounced on the left - mild atrophy of the amygdala - mild atrophy of the hippocampus - mild left atrophy of the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the inf. lateral ventricle - mild enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the external csf - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0045_MR_t1_mprage_S3_DIS3D_br_raw_20110718072112237_47_S115028_I245220

On a T1-weighted brain MRI of a 59-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0175_MR_T1_mprage_S3_DIS3D_br_raw_20140701125948453_146_S223924_I434014

On a T1-weighted brain MRI of a 60-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of insular cortex on anterior insula - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_2_S_0017_MR_MT1__GradWarp__N3m_Br_20120509155907422_S147140_I302626

On a T1-weighted brain MRI of a 61-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the occipital lobe, with focal volume reduction observed in the following subregions: lingual gyrus (moderate), cuneus (mild) and sup. occipital gyrus (mild) - mild focal atrophy of temporal lobe on planum polare - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0235_MR_t1_mprage__br_raw_20160902135026421_139_S495650_I771798

On a T1-weighted brain MRI of a 68-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on posterior orbital gyrus - atrophies of temporal lobe on inf. temporal gyrus (mild) and sup. temporal gyrus (mild) - mild focal atrophy of occipital lobe on lingual gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_2_S_0008_MR_MT1__GradWarp__N3m_Br_20111229190047421_S133665_I274730

On a T1-weighted brain MRI of a 64-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on sup. temporal gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild left atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0153_MR_T1_mprage_S3_DIS3D_br_raw_20140612232122447_36_S222103_I430675

On a T1-weighted brain MRI of a 55-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on sup. temporal gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0010_MR_T1_MPRAGE_long_S4_DIS3D__br_raw_20110204151510599_49_S99062_I216003

On a T1-weighted brain MRI of a 81-year-old male subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: angular gyrus (mild) - atrophies of frontal lobe on gyrus rectus (moderate), precentral gyrus (moderate) and precentral gyrus medial segment (mild) - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - moderate bilateral atrophy of the putamen, more pronounced on the left - mild atrophy of the thalamus, more pronounced on the left - mild left atrophy of the caudate - mild left atrophy of the pallidum - mild left atrophy of the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0081_MR_T1_mprage_S3_DIS3D_br_raw_20120307021952212_143_S143093_I288731

On a T1-weighted brain MRI of a 60-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the frontal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: posterior orbital gyrus (moderate) and middle frontal gyrus (mild) - mild focal atrophy of limbic cortex on anterior cingulate gyrus - mild focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - moderate bilateral atrophy of the caudate, more pronounced on the right - mild bilateral atrophy of the putamen, more pronounced on the right - mild bilateral atrophy of the accumbens - mild atrophy of the pallidum, more pronounced on the right - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0102_MR_T1_mprage_S3_DIS3D_br_raw_20170816161439198_36_S596667_I889712

On a T1-weighted brain MRI of a 71-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, with focal volume reduction observed in the following subregions: middle frontal gyrus (severe), precentral gyrus (moderate), frontal pole (mild), sup. frontal gyrus (mild), supplementary motor cortex (mild) and gyrus rectus (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) and middle cingulate gyrus (mild) - atrophies of insular cortex on anterior insula (mild) and frontal operculum (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the pallidum, more pronounced on the left - severe bilateral atrophy of the ventral dc, more pronounced on the left - severe bilateral atrophy of the thalamus, more pronounced on the left - moderate bilateral atrophy of the putamen, more pronounced on the left - mild atrophy of the hippocampus - mild left atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain For the ventricles: - mild left enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - severe enlargement of the external csf - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0119_MR_t1_mprage_S3_DIS3D_br_raw_20170814185756776_15_S594508_I887000

On a T1-weighted brain MRI of a 70-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on middle frontal gyrus (mild) and precentral gyrus (mild) - mild focal atrophy of parietal lobe on postcentral gyrus - mild focal atrophy of insular cortex on anterior insula - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - mild bilateral atrophy of the pallidum - mild bilateral atrophy of the caudate - mild bilateral atrophy of the thalamus - mild bilateral atrophy of the ventral dc - mild atrophy of the hippocampus - mild atrophy of the putamen - mild left atrophy of the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0332_MR_t1_mprage_short__br_raw_20170628200022329_22_S577253_I866807

On a T1-weighted brain MRI of a 55-year-old male subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: postcentral gyrus medial segment (mild) and sup. parietal lobule (mild) - mild bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) and entorhinal area (mild) - mild focal atrophy of frontal lobe on middle frontal gyrus - mild focal atrophy of temporal lobe on planum polare - mild focal atrophy of occipital lobe on inf. occipital gyrus - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the accumbens, more pronounced on the right - moderate bilateral atrophy of the caudate - mild bilateral atrophy of the pallidum - mild bilateral atrophy of the putamen - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - moderate bilateral enlargement of the inf. lateral ventricle - mild right enlargement of the lateral ventricle - severe enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the external csf

FTD

NIFD_1_S_0347_MR_T1_mprage_S17_DIS3D__br_raw_20170629034809877_28_S578320_I868238

On a T1-weighted brain MRI of a 61-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (severe), fusiform gyrus (severe), inf. temporal gyrus (severe), middle temporal gyrus (moderate) and planum polare (mild) - severe bilateral atrophy of the limbic cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (moderate) and entorhinal area (mild) - mild bilateral atrophy of the occipital lobe, with focal volume reduction observed in the following subregions: calcarine cortex (mild) and cuneus (mild) - mild atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior insula (moderate) and posterior insula (mild) - mild focal atrophy of frontal lobe on middle frontal gyrus - no evidence of atrophy in the parietal lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - moderate bilateral atrophy of the putamen, more pronounced on the left - moderate bilateral atrophy of the accumbens - moderate bilateral atrophy of the hippocampus - no evidence of atrophy in the basal forebrain - mild bilateral atrophy of the thalamus, more pronounced on the left - mild atrophy of the caudate, more pronounced on the left - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - moderate bilateral enlargement of the lateral ventricle - severe enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_2_S_0030_MR_MT1__GradWarp__N3m_Br_20130111113347184_S179870_I354749

On a T1-weighted brain MRI of a 65-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: sup. frontal gyrus (severe), middle frontal gyrus (moderate), medial orbital gyrus (moderate), frontal pole (moderate), medial frontal cortex (mild), opercular inf. frontal gyrus (mild), lateral orbital gyrus (mild), supplementary motor cortex (mild), gyrus rectus (mild) and triangular inf. frontal gyrus (mild) - moderate bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (severe), frontal operculum (mild) and posterior insula (mild) - mild atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: sup. temporal gyrus (mild) - severe focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the accumbens, more pronounced on the left - severe bilateral atrophy of the putamen, more pronounced on the left - mild atrophy of the amygdala, more pronounced on the left - moderate left atrophy of the hippocampus - mild left atrophy of the thalamus - no evidence of atrophy in the pallidum - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc For the ventricles: - severe left enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - severe enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_3_S_0008_MR_T1_mprage_ND_br_raw_20160518225653834_34_S442955_I709965

On a T1-weighted brain MRI of a 76-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the frontal lobe, with focal volume reduction observed in the following subregions: precentral gyrus (moderate), middle frontal gyrus (mild) and sup. frontal gyrus (mild) - atrophies of limbic cortex on anterior cingulate gyrus (mild) and posterior cingulate gyrus (mild) - moderate focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - moderate bilateral atrophy of the ventral dc, more pronounced on the left - mild atrophy of the pallidum, more pronounced on the left - moderate left atrophy of the thalamus - mild left atrophy of the caudate - mild left atrophy of the accumbens - no evidence of atrophy in the putamen - no evidence of atrophy in the hippocampus - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain For the ventricles: - mild left enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - severe enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0047_MR_T1_mprage_S3_DIS3D_br_raw_20170815144529953_108_S595607_I888297

On a T1-weighted brain MRI of a 74-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of parietal lobe on postcentral gyrus - mild focal atrophy of limbic cortex on parahippocampal gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0164_MR_T1_mprage_S3_DIS3D_br_raw_20140701122630674_112_S223782_I433851

On a T1-weighted brain MRI of a 59-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (mild), posterior insula (mild) and frontal operculum (mild) - mild focal atrophy of frontal lobe on triangular inf. frontal gyrus - mild focal atrophy of temporal lobe on planum polare - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0191_MR_T1_mprage_S3_DIS3D_br_raw_20170817111331184_37_S597619_I891027

On a T1-weighted brain MRI of a 50-year-old male subject, we observed the following: For the cerebral cortex: - moderate focal atrophy of parietal lobe on angular gyrus - atrophies of occipital lobe on inf. occipital gyrus (mild) and sup. occipital gyrus (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0237_MR_t1_mprage__br_raw_20160902142657075_120_S495712_I771873

On a T1-weighted brain MRI of a 68-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: precuneus (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0252_MR_t1_mprage__br_raw_20160902174515098_32_S496041_I772252

On a T1-weighted brain MRI of a 72-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on inf. temporal gyrus - mild focal atrophy of occipital lobe on occipital fusiform gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0271_MR_T1_mprage_S3_DIS3D_br_raw_20160903180503381_81_S496532_I772811

On a T1-weighted brain MRI of a 68-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on opercular inf. frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0273_MR_t1_mprage_short__br_raw_20160903183136298_99_S496584_I772871

On a T1-weighted brain MRI of a 67-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: postcentral gyrus medial segment (mild) and precuneus (mild) - mild focal atrophy of occipital lobe on lingual gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild right atrophy of the amygdala - mild right atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0283_MR_t1_mprage__br_raw_20160903210340051_117_S496751_I773062

On a T1-weighted brain MRI of a 81-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe - atrophies of frontal lobe on gyrus rectus (moderate), posterior orbital gyrus (mild), orbital inf. frontal gyrus (mild) and medial frontal cortex (mild) - mild focal atrophy of limbic cortex on posterior cingulate gyrus - mild focal atrophy of insular cortex on anterior insula - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - mild atrophy of the hippocampus, more pronounced on the left - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

ADNI_022_S_4291_MR_MPRAGE_br_raw_20111130090916449_95_S131264_I269153

On a T1-weighted brain MRI of a 76-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on sup. frontal gyrus - atrophies of temporal lobe on planum temporale (mild) and sup. temporal gyrus (mild) - mild focal atrophy of parietal lobe on postcentral gyrus medial segment - mild focal atrophy of occipital lobe on occipital pole - mild focal atrophy of insular cortex on parietal operculum - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - mild right atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - moderate bilateral enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_153_S_4125_MR_MPRAGE_br_raw_20110720110937386_57_S115446_I245820

On a T1-weighted brain MRI of a 76-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_031_S_4024_MR_MPRAGE_br_raw_20110425135648715_88_S105088_I228879

On a T1-weighted brain MRI of a 56-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the parietal lobe - moderate focal atrophy of frontal lobe on sup. frontal gyrus - atrophies of temporal lobe on middle temporal gyrus (mild) and inf. temporal gyrus (mild) - mild focal atrophy of occipital lobe on middle occipital gyrus - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the hippocampus - mild atrophy of the amygdala, more pronounced on the left - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_007_S_4637_MR_Accelerated_SAG_IR-SPGR__br_raw_20120405173505776_125_S146554_I296253

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_098_S_4003_MR_Accelerated_Sag_IR-SPGR__br_raw_20110322131336182_62_S102158_I224611

On a T1-weighted brain MRI of a 72-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of temporal lobe on planum polare (mild) and planum temporale (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_022_S_4173_MR_MPRAGE_br_raw_20110914160652081_58_S122033_I255992

On a T1-weighted brain MRI of a 70-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on middle frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_016_S_5032_MR_Accelerated_SAG_IR-SPGR__br_raw_20121130134021740_63_S175940_I348593

On a T1-weighted brain MRI of a 78-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on medial frontal cortex - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate atrophy of the amygdala, more pronounced on the right - mild bilateral atrophy of the accumbens - no evidence of atrophy in the ventral dc - no evidence of atrophy in the pallidum - no evidence of atrophy in the hippocampus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_041_S_4060_MR_MPRAGE_br_raw_20110601153106894_30_S110364_I238383

On a T1-weighted brain MRI of a 85-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on subcallosal area - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the amygdala - no evidence of atrophy in the putamen - no evidence of atrophy in the caudate - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_073_S_4795_MR_MPRAGE_br_raw_20120606151852821_163_S153047_I308459

On a T1-weighted brain MRI of a 62-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe - atrophies of frontal lobe on posterior orbital gyrus (mild) and orbital inf. frontal gyrus (mild) - mild focal atrophy of temporal lobe on sup. temporal gyrus - mild focal atrophy of limbic cortex on parahippocampal gyrus - atrophies of insular cortex on posterior insula (mild) and parietal operculum (mild) - no evidence of atrophy in the occipital lobe For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc - no evidence of atrophy in the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_011_S_4075_MR_MPRAGE_br_raw_20110610163924528_171_S111256_I239736

On a T1-weighted brain MRI of a 74-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: precuneus (mild) - mild focal atrophy of frontal lobe on medial orbital gyrus - mild focal atrophy of occipital lobe on lingual gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_114_S_4379_MR_MPRAGE_br_raw_20120119121248826_98_S136145_I277487

On a T1-weighted brain MRI of a 88-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: temporal pole (moderate) and inf. temporal gyrus (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the accumbens - moderate bilateral atrophy of the amygdala - mild bilateral atrophy of the pallidum - mild atrophy of the putamen, more pronounced on the left - no evidence of atrophy in the ventral dc - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_073_S_5023_MR_MPRAGE_br_raw_20131009133645228_136_S203499_I393941

On a T1-weighted brain MRI of a 64-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on posterior orbital gyrus - mild focal atrophy of parietal lobe on postcentral gyrus medial segment - mild focal atrophy of insular cortex on posterior insula - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the putamen - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_126_S_4686_MR_Accelerated_Sag_IR-SPGR__br_raw_20120427123703300_117_S148519_I300822

On a T1-weighted brain MRI of a 72-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on medial frontal cortex - mild focal atrophy of parietal lobe on postcentral gyrus medial segment - mild focal atrophy of occipital lobe on calcarine cortex - mild focal atrophy of limbic cortex on entorhinal area - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the temporal lobe For the subcortical structures: - moderate bilateral atrophy of the amygdala - mild atrophy of the hippocampus, more pronounced on the left - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_002_S_4213_MR_MPRAGE_br_raw_20110903090753647_129_S121168_I254582

On a T1-weighted brain MRI of a 79-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN