Datasets:

andrewzamai

/

CNADFTD-ADNI2NIFD-AN-fold-0-gathered-0234

like 0

ADNI_010_S_4442_MR_MPRAGE_br_raw_20120210180208528_27_S140482_I283915

On a T1-weighted brain MRI of a 75-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe - mild focal atrophy of frontal lobe on medial orbital gyrus - moderate focal atrophy of occipital lobe on inf. occipital gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild left atrophy of the accumbens - no evidence of atrophy in the pallidum - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_016_S_4097_MR_Accelerated_SAG_IR-SPGR__br_raw_20110707114713801_46_S113795_I243557

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on triangular inf. frontal gyrus (mild) and precentral gyrus medial segment (mild) - mild focal atrophy of parietal lobe on postcentral gyrus - mild focal atrophy of limbic cortex on posterior cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum For the ventricles: - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_130_S_5006_MR_MPRAGE_br_raw_20121130100341274_49_S175869_I348490

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the frontal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: medial frontal cortex (mild), middle frontal gyrus (mild), sup. frontal gyrus (mild), gyrus rectus (mild) and medial orbital gyrus (mild) - mild bilateral atrophy of the temporal lobe, with focal volume reduction observed in the following subregions: planum temporale (moderate) and temporal pole (mild) - mild bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) and posterior cingulate gyrus (mild) - mild bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (mild) and parietal operculum (mild) - mild focal atrophy of parietal lobe on angular gyrus - no evidence of atrophy in the occipital lobe For the subcortical structures: - moderate bilateral atrophy of the accumbens, more pronounced on the right - moderate bilateral atrophy of the amygdala - no evidence of atrophy in the basal forebrain - moderate bilateral atrophy of the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the caudate - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_130_S_4343_MR_MPRAGE_br_raw_20111114125456890_31_S129057_I266217

On a T1-weighted brain MRI of a 80-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: angular gyrus (moderate) - mild focal atrophy of temporal lobe on sup. temporal gyrus - mild focal atrophy of insular cortex on posterior insula - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the caudate - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_073_S_4853_MR_MPRAGE_br_raw_20120711181405636_32_S157321_I315948

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the frontal lobe, with focal volume reduction observed in the following subregions: sup. frontal gyrus (mild) and sup. frontal gyrus medial segment (mild) - mild atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: middle temporal gyrus (mild) and sup. temporal gyrus (mild) - mild atrophy of the limbic cortex - atrophies of insular cortex on central operculum (mild) and posterior insula (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - mild atrophy of the amygdala, more pronounced on the right - mild atrophy of the hippocampus, more pronounced on the right - mild bilateral atrophy of the ventral dc - mild atrophy of the accumbens, more pronounced on the right - no evidence of atrophy in the putamen - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_037_S_4879_MR_MPRAGE_br_raw_20120913121552870_142_S167309_I333832

On a T1-weighted brain MRI of a 80-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: sup. parietal lobule (severe) - mild focal atrophy of limbic cortex on entorhinal area - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc - mild atrophy of the amygdala - mild atrophy of the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the thalamus For the ventricles: - mild right enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_041_S_4200_MR_MPRAGE_br_raw_20110922151324186_72_S123030_I257470

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on fusiform gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_130_S_4997_MR_MPRAGE_br_raw_20121120141641968_22_S175145_I347410

On a T1-weighted brain MRI of a 61-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the parietal lobe - mild focal atrophy of frontal lobe on middle frontal gyrus - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_116_S_4625_MR_MPRAGE_br_raw_20120405131840016_174_S146475_I296138

On a T1-weighted brain MRI of a 64-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of parietal lobe on precuneus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala - no evidence of atrophy in the ventral dc - no evidence of atrophy in the thalamus - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the pallidum For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_116_S_4092_MR_MPRAGE_br_raw_20110624151136233_164_S112544_I241692

On a T1-weighted brain MRI of a 82-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of parietal lobe on sup. parietal lobule - mild focal atrophy of occipital lobe on occipital pole - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild left atrophy of the thalamus - mild left atrophy of the basal forebrain - no evidence of atrophy in the putamen - no evidence of atrophy in the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_137_S_4482_MR_MPRAGE_br_raw_20120216103107707_132_S140958_I285105

On a T1-weighted brain MRI of a 78-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on middle frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 4th ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle

CN

ADNI_135_S_4598_MR_MPRAGE_br_raw_20120320143741415_135_S144209_I291138

On a T1-weighted brain MRI of a 66-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on posterior orbital gyrus - mild focal atrophy of limbic cortex on posterior cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the hippocampus, more pronounced on the left - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_003_S_4288_MR_Accelerated_SAG_IR-SPGR__br_raw_20111025121215195_94_S126256_I262283

On a T1-weighted brain MRI of a 73-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the hippocampus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_116_S_4195_MR_MPRAGE_br_raw_20110901175610510_89_S121073_I254248

On a T1-weighted brain MRI of a 63-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: inf. temporal gyrus (mild) and temporal pole (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - mild atrophy of the hippocampus, more pronounced on the right - mild right atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_128_S_5123_MR_MPRAGE_br_raw_20130625131829943_43_S193357_I378115

On a T1-weighted brain MRI of a 74-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the temporal lobe, with focal volume reduction observed in the following subregions: transverse temporal gyrus (mild), fusiform gyrus (mild) and sup. temporal gyrus (mild) - atrophies of frontal lobe on precentral gyrus (mild) and posterior orbital gyrus (mild) - mild focal atrophy of parietal lobe on postcentral gyrus - mild focal atrophy of occipital lobe on inf. occipital gyrus - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the limbic cortex For the subcortical structures: - severe bilateral atrophy of the hippocampus - no evidence of atrophy in the basal forebrain - mild left atrophy of the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_116_S_4010_MR_MPRAGE_br_raw_20110401094558289_2_S102845_I225667

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on gyrus rectus (mild) and medial frontal cortex (mild) - atrophies of temporal lobe on transverse temporal gyrus (moderate) and sup. temporal gyrus (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the hippocampus - mild left atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_100_S_4469_MR_MPRAGE_br_raw_20120309113839177_24_S143466_I289564

On a T1-weighted brain MRI of a 67-year-old male subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the basal forebrain, more pronounced on the right - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_027_S_4801_MR_Accelerated_SAG_IR-SPGR__br_raw_20120703090719222_105_S156382_I314033

On a T1-weighted brain MRI of a 78-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on medial frontal cortex - mild focal atrophy of occipital lobe on cuneus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the hippocampus, more pronounced on the left - mild right atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_036_S_5063_MR_MPRAGE_br_raw_20130118120907075_34_S180473_I355515

On a T1-weighted brain MRI of a 72-year-old female subject, we observed the following: For the cerebral cortex: - moderate atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: middle temporal gyrus (moderate) and sup. temporal gyrus (mild) - mild atrophy of the parietal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: angular gyrus (moderate) - mild bilateral atrophy of the occipital lobe, with focal volume reduction observed in the following subregions: middle occipital gyrus (moderate), lingual gyrus (mild) and calcarine cortex (mild) - mild bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: posterior insula (moderate) and anterior insula (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (moderate) - no evidence of atrophy in the frontal lobe For the subcortical structures: - moderate bilateral atrophy of the accumbens - moderate bilateral atrophy of the amygdala, more pronounced on the left - no evidence of atrophy in the basal forebrain - mild left atrophy of the putamen - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - moderate bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - severe enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_127_S_4645_MR_Accelerated_Sag_IR-SPGR__br_raw_20120404151150404_76_S146136_I295597

On a T1-weighted brain MRI of a 76-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_021_S_4421_MR_Accelerated_Sag_IR-SPGR__br_raw_20111221105845600_170_S134211_I273577

On a T1-weighted brain MRI of a 75-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on middle temporal gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_003_S_4441_MR_Accelerated_SAG_IR-SPGR__br_raw_20120110130312852_183_S135914_I277118

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of occipital lobe on sup. occipital gyrus - mild focal atrophy of limbic cortex on posterior cingulate gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - mild left atrophy of the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_130_S_4990_MR_MPRAGE_br_raw_20121029151935426_15_S172518_I342911

On a T1-weighted brain MRI of a 76-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the parietal lobe - mild atrophy of the frontal lobe, with focal volume reduction observed in the following subregions: opercular inf. frontal gyrus (moderate), medial orbital gyrus (mild) and sup. frontal gyrus (mild) - mild focal atrophy of temporal lobe on middle temporal gyrus - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the accumbens - mild atrophy of the putamen, more pronounced on the right - mild atrophy of the amygdala - mild atrophy of the caudate - no evidence of atrophy in the basal forebrain - mild left atrophy of the pallidum - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild right enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_013_S_5071_MR_MPRAGE_br_raw_20130215130506824_28_S182443_I360324

On a T1-weighted brain MRI of a 77-year-old male subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on posterior orbital gyrus (moderate), gyrus rectus (mild) and medial orbital gyrus (mild) - mild focal atrophy of occipital lobe on occipital pole - mild focal atrophy of limbic cortex on parahippocampal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the thalamus - mild atrophy of the amygdala, more pronounced on the left - no evidence of atrophy in the ventral dc - mild left atrophy of the hippocampus - mild left atrophy of the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_128_S_4832_MR_MPRAGE_br_raw_20120710092632233_36_S157109_I315671

On a T1-weighted brain MRI of a 70-year-old male subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on lateral orbital gyrus (moderate) and medial frontal cortex (mild) - mild focal atrophy of temporal lobe on transverse temporal gyrus - mild focal atrophy of occipital lobe on cuneus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_006_S_4485_MR_MPRAGE_br_raw_20120201124039752_139_S139148_I281882

On a T1-weighted brain MRI of a 74-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: angular gyrus (mild) - mild focal atrophy of limbic cortex on entorhinal area - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - moderate enlargement of the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

ADNI_073_S_4552_MR_MPRAGE_br_raw_20120215154934047_48_S140944_I285080

On a T1-weighted brain MRI of a 64-year-old male subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on opercular inf. frontal gyrus (moderate) and triangular inf. frontal gyrus (mild) - mild focal atrophy of occipital lobe on middle occipital gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_127_S_5067_MR_Accelerated_Sag_IR-FSPGR_br_raw_20130204134411723_7_S181409_I357660

On a T1-weighted brain MRI of a 81-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on medial frontal cortex - mild focal atrophy of temporal lobe on planum polare - atrophies of limbic cortex on parahippocampal gyrus (moderate) and entorhinal area (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the amygdala - moderate bilateral atrophy of the ventral dc - moderate bilateral atrophy of the hippocampus, more pronounced on the left - mild bilateral atrophy of the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - mild enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_098_S_4201_MR_Accelerated_Sag_IR-SPGR__br_raw_20110915152919253_90_S122171_I256181

On a T1-weighted brain MRI of a 64-year-old female subject, we observed the following: For the cerebral cortex: - moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: middle temporal gyrus (severe) and sup. temporal gyrus (moderate) - mild focal atrophy of occipital lobe on middle occipital gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala, more pronounced on the right - mild atrophy of the accumbens, more pronounced on the right - no evidence of atrophy in the thalamus - no evidence of atrophy in the putamen - no evidence of atrophy in the caudate - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_016_S_4952_MR_Accelerated_SAG_IR-SPGR__br_raw_20121002132023568_140_S169422_I337802

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on triangular inf. frontal gyrus (mild) and supplementary motor cortex (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_099_S_4994_MR_MPRAGE_br_raw_20121203123842054_174_S176117_I348826

On a T1-weighted brain MRI of a 85-year-old male subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: sup. parietal lobule (mild) - mild atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: inf. temporal gyrus (moderate), temporal pole (moderate) and planum temporale (mild) - mild focal atrophy of frontal lobe on precentral gyrus medial segment - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala, more pronounced on the left - moderate left atrophy of the hippocampus - mild left atrophy of the caudate - mild left atrophy of the putamen - no evidence of atrophy in the thalamus - mild left atrophy of the accumbens - no evidence of atrophy in the ventral dc - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the pallidum For the ventricles: - moderate left enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_123_S_4526_MR_MPRAGE_br_raw_20120209093528861_37_S140267_I283603

On a T1-weighted brain MRI of a 80-year-old male subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the amygdala, more pronounced on the left - mild atrophy of the hippocampus, more pronounced on the left - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_130_S_4352_MR_MPRAGE_br_raw_20111121102623843_152_S130237_I267711

On a T1-weighted brain MRI of a 84-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on sup. frontal gyrus - mild focal atrophy of occipital lobe on occipital fusiform gyrus - mild focal atrophy of limbic cortex on middle cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_2_S_0007_MR_MT1__GradWarp__N3m_Br_20111229185843831_S133650_I274728

On a T1-weighted brain MRI of a 65-year-old male subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on gyrus rectus (mild) and lateral orbital gyrus (mild) - mild focal atrophy of temporal lobe on temporal pole - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild bilateral enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0127_MR_T1_mprage_S3_DIS3D_br_raw_20170817113930950_131_S597781_I891241

On a T1-weighted brain MRI of a 61-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (severe), fusiform gyrus (moderate), middle temporal gyrus (mild), inf. temporal gyrus (mild) and sup. temporal gyrus (mild) - moderate bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: parahippocampal gyrus (moderate), entorhinal area (moderate) and anterior cingulate gyrus (mild) - mild atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: posterior insula (moderate) and anterior insula (mild) - atrophies of frontal lobe on gyrus rectus (mild) and orbital inf. frontal gyrus (mild) - atrophies of occipital lobe on occipital fusiform gyrus (mild) and inf. occipital gyrus (mild) - no evidence of atrophy in the parietal lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - moderate bilateral atrophy of the hippocampus - mild bilateral atrophy of the accumbens - no evidence of atrophy in the basal forebrain - mild atrophy of the putamen, more pronounced on the left - mild left atrophy of the thalamus - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0029_MR_t1_mprage_S4_DIS3D_br_raw_20110209101901199_30_S99286_I216392

On a T1-weighted brain MRI of a 58-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (severe) and frontal operculum (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (moderate) - atrophies of frontal lobe on sup. frontal gyrus (mild), gyrus rectus (mild) and medial frontal cortex (mild) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the accumbens, more pronounced on the left - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the pallidum, more pronounced on the left - severe bilateral atrophy of the putamen, more pronounced on the left - severe bilateral atrophy of the hippocampus, more pronounced on the right - moderate bilateral atrophy of the amygdala - mild bilateral atrophy of the thalamus - mild bilateral atrophy of the ventral dc - no evidence of atrophy in the basal forebrain For the ventricles: - moderate bilateral enlargement of the inf. lateral ventricle - mild enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0209_MR_T1_mprage_S3_DIS3D_br_raw_20140901123615201_24_S229648_I442043

On a T1-weighted brain MRI of a 58-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: sup. frontal gyrus (moderate), opercular inf. frontal gyrus (moderate), triangular inf. frontal gyrus (mild), posterior orbital gyrus (mild), medial frontal cortex (mild) and middle frontal gyrus (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (moderate) - mild focal atrophy of temporal lobe on temporal pole - mild focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the caudate - moderate bilateral atrophy of the putamen, more pronounced on the right - mild bilateral atrophy of the accumbens - mild bilateral atrophy of the thalamus - mild atrophy of the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - mild bilateral enlargement of the lateral ventricle - mild enlargement of the inf. lateral ventricle - moderate enlargement of the 3rd ventricle - mild enlargement of the external csf - no evidence of enlargements in the 4th ventricle

FTD

NIFD_2_S_0002_MR_MT1__GradWarp__N3m_Br_20111229184614074_S133938_I274719

On a T1-weighted brain MRI of a 64-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: gyrus rectus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), frontal pole (moderate), middle frontal gyrus (moderate), sup. frontal gyrus medial segment (severe), medial orbital gyrus (moderate), sup. frontal gyrus (moderate), medial frontal cortex (mild), posterior orbital gyrus (mild) and opercular inf. frontal gyrus (mild) - moderate atrophy of the insular cortex, more pronounced on the right, with focal volume reduction observed in the following subregions: anterior insula (severe) and frontal operculum (moderate) - mild atrophy of the limbic cortex, more pronounced on the right, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (severe) - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the caudate, more pronounced on the right - severe bilateral atrophy of the pallidum, more pronounced on the right - severe bilateral atrophy of the accumbens, more pronounced on the right - severe bilateral atrophy of the putamen, more pronounced on the right - mild atrophy of the thalamus, more pronounced on the right - mild atrophy of the hippocampus, more pronounced on the right - mild right atrophy of the ventral dc - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the amygdala For the ventricles: - severe enlargement of the inf. lateral ventricle, more pronounced on the right - mild enlargement of the lateral ventricle, more pronounced on the right - moderate enlargement of the 3rd ventricle - moderate enlargement of the external csf - no evidence of enlargements in the 4th ventricle

FTD

NIFD_3_S_0002_MR_T1_mprage__br_raw_20160518171333316_118_S442724_I709714

On a T1-weighted brain MRI of a 64-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (severe), fusiform gyrus (severe), inf. temporal gyrus (moderate), middle temporal gyrus (moderate) and sup. temporal gyrus (mild) - mild atrophy of the limbic cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: entorhinal area (moderate) and parahippocampal gyrus (mild) - mild atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior insula (severe) and posterior insula (moderate) - mild focal atrophy of frontal lobe on anterior orbital gyrus - moderate focal atrophy of parietal lobe on angular gyrus - moderate focal atrophy of occipital lobe on occipital fusiform gyrus For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - moderate bilateral atrophy of the putamen, more pronounced on the left - mild bilateral atrophy of the caudate, more pronounced on the left - mild atrophy of the accumbens, more pronounced on the left - mild atrophy of the hippocampus, more pronounced on the left - mild atrophy of the pallidum, more pronounced on the left - mild left atrophy of the ventral dc - no evidence of atrophy in the thalamus - no evidence of atrophy in the basal forebrain For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_3_S_0012_MR_T1_mprage_S3_DIS3D_br_raw_20160520111537809_160_S212086_I413590

On a T1-weighted brain MRI of a 64-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior insula (moderate), frontal operculum (moderate) and parietal operculum (mild) - moderate atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: frontal pole (mild), orbital inf. frontal gyrus (mild), middle frontal gyrus (mild), posterior orbital gyrus (mild), opercular inf. frontal gyrus (mild) and lateral orbital gyrus (mild) - moderate atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (moderate), middle temporal gyrus (mild) and inf. temporal gyrus (mild) - mild atrophy of the limbic cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - mild atrophy of the amygdala, more pronounced on the left - mild left atrophy of the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the pallidum - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the hippocampus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0103_MR_T1_mprage_S3_DIS3D_br_raw_20120914122704384_3_S167579_I334274

On a T1-weighted brain MRI of a 57-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: gyrus rectus (severe), medial orbital gyrus (severe), lateral orbital gyrus (severe), medial frontal cortex (severe), sup. frontal gyrus medial segment (severe), frontal pole (moderate), orbital inf. frontal gyrus (moderate), posterior orbital gyrus (moderate), middle frontal gyrus (mild), subcallosal area (mild), sup. frontal gyrus (mild), opercular inf. frontal gyrus (mild) and anterior orbital gyrus (mild) - severe bilateral atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: inf. temporal gyrus (severe), temporal pole (severe), middle temporal gyrus (severe) and fusiform gyrus (mild) - severe bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (severe) and middle cingulate gyrus (mild) - moderate bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (severe), posterior insula (moderate) and frontal operculum (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the right - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the putamen, more pronounced on the left - severe bilateral atrophy of the accumbens - moderate bilateral atrophy of the pallidum, more pronounced on the left - moderate bilateral atrophy of the thalamus, more pronounced on the left - mild atrophy of the hippocampus, more pronounced on the right - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - moderate bilateral enlargement of the lateral ventricle - severe enlargement of the external csf - moderate enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0084_MR_T1_mprage_S5_DIS3D_br_raw_20120819205904146_39_S161569_I324836

On a T1-weighted brain MRI of a 53-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (severe), inf. temporal gyrus (mild) and middle temporal gyrus (mild) - mild atrophy of the limbic cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) - atrophies of frontal lobe on medial frontal cortex (mild) and gyrus rectus (mild) - mild focal atrophy of parietal lobe on precuneus - mild focal atrophy of insular cortex on anterior insula - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the accumbens, more pronounced on the left - moderate atrophy of the amygdala, more pronounced on the left - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the thalamus - mild left atrophy of the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the pallidum - no evidence of atrophy in the caudate - no evidence of atrophy in the ventral dc For the ventricles: - mild left enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0067_MR_t1_mprage_S6_DIS3D_br_raw_20111209120245536_154_S132398_I270856

On a T1-weighted brain MRI of a 78-year-old male subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on posterior orbital gyrus (mild), medial frontal cortex (mild) and middle frontal gyrus (mild) - mild focal atrophy of temporal lobe on middle temporal gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the amygdala, more pronounced on the left - moderate bilateral atrophy of the accumbens - no evidence of atrophy in the basal forebrain - mild bilateral atrophy of the caudate, more pronounced on the left - mild atrophy of the putamen, more pronounced on the left - mild atrophy of the pallidum, more pronounced on the left - mild left atrophy of the thalamus - mild left atrophy of the hippocampus - no evidence of atrophy in the ventral dc For the ventricles: - moderate bilateral enlargement of the inf. lateral ventricle - mild left enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the external csf - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0217_MR_T1_mprage_S3_DIS3D_br_raw_20170817134937636_129_S598229_I891831

On a T1-weighted brain MRI of a 56-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (mild) - atrophies of frontal lobe on orbital inf. frontal gyrus (mild) and posterior orbital gyrus (mild) - mild focal atrophy of occipital lobe on inf. occipital gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0279_MR_t1_mprage__br_raw_20160903204551965_44_S496713_I773020

On a T1-weighted brain MRI of a 62-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on medial frontal cortex - mild focal atrophy of temporal lobe on inf. temporal gyrus - mild focal atrophy of occipital lobe on inf. occipital gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the pallidum - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0295_MR_t1_mprage__br_raw_20170628140904383_36_S576514_I865882

On a T1-weighted brain MRI of a 61-year-old male subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on lateral orbital gyrus (mild), precentral gyrus (mild) and sup. frontal gyrus (mild) - mild focal atrophy of parietal lobe on angular gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0254_MR_t1_mprage__br_raw_20160902175658994_31_S496062_I772280

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the putamen, more pronounced on the left - mild atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0266_MR_t1_mprage__br_raw_20160902212027546_148_S496336_I772588

On a T1-weighted brain MRI of a 68-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild right atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0288_MR_t1_mprage__br_raw_20170814180736340_14_S594408_I886878

On a T1-weighted brain MRI of a 64-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on planum temporale - mild focal atrophy of limbic cortex on parahippocampal gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the caudate - mild left atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0096_MR_T1_mprage_S3_DIS3D_br_raw_20170817133934845_74_S598211_I891811

On a T1-weighted brain MRI of a 69-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on middle frontal gyrus - mild focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - mild atrophy of the thalamus, more pronounced on the right - no evidence of atrophy in the putamen - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0169_MR_T1_mprage_S3_DIS3D_br_raw_20140701110602779_92_S223672_I433733

On a T1-weighted brain MRI of a 74-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: central operculum (mild) - moderate focal atrophy of frontal lobe on sup. frontal gyrus - atrophies of temporal lobe on sup. temporal gyrus (mild) and planum temporale (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - moderate bilateral atrophy of the hippocampus, more pronounced on the right - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0333_MR_T1_mprage_S3_DIS3D_br_raw_20170628211504795_43_S577375_I866968

On a T1-weighted brain MRI of a 65-year-old male subject, we observed the following: For the cerebral cortex: - moderate atrophy of the frontal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: middle frontal gyrus (moderate), sup. frontal gyrus (moderate), gyrus rectus (mild), sup. frontal gyrus medial segment (mild) and posterior orbital gyrus (mild) - mild focal atrophy of temporal lobe on inf. temporal gyrus - atrophies of limbic cortex on anterior cingulate gyrus (mild) and middle cingulate gyrus (mild) - mild focal atrophy of insular cortex on anterior insula - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - moderate bilateral atrophy of the caudate, more pronounced on the right - mild bilateral atrophy of the putamen, more pronounced on the right - mild right atrophy of the amygdala - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus For the ventricles: - mild right enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_2_S_0013_MR_MT1__GradWarp__N3m_Br_20111229190902340_S134506_I274738

On a T1-weighted brain MRI of a 69-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: middle temporal gyrus (severe), temporal pole (severe), fusiform gyrus (moderate), inf. temporal gyrus (moderate) and planum polare (mild) - mild atrophy of the parietal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: postcentral gyrus medial segment (mild) and angular gyrus (mild) - mild atrophy of the limbic cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (mild) - mild focal atrophy of frontal lobe on gyrus rectus - atrophies of occipital lobe on middle occipital gyrus (moderate) and occipital fusiform gyrus (mild) - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - no evidence of atrophy in the ventral dc - mild atrophy of the hippocampus, more pronounced on the left - no evidence of atrophy in the thalamus - mild atrophy of the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the putamen - no evidence of atrophy in the pallidum - no evidence of atrophy in the caudate For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_2_S_0032_MR_MT1__GradWarp__N3m_Br_20130613083444087_S191547_I376358

On a T1-weighted brain MRI of a 58-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on inf. temporal gyrus - mild focal atrophy of occipital lobe on sup. occipital gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the hippocampus - mild right atrophy of the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0160_MR_T1_mprage_S3_DIS3D_br_raw_20140701124951616_139_S223881_I433960

On a T1-weighted brain MRI of a 64-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on frontal pole (mild) and subcallosal area (mild) - mild focal atrophy of temporal lobe on sup. temporal gyrus - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild left atrophy of the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0190_MR_T1_mprage_S3_DIS3D_br_raw_20170816151005927_150_S596443_I889392

On a T1-weighted brain MRI of a 53-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on posterior orbital gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0213_MR_T1_mprage_S3_DIS3D_br_raw_20170815200354578_115_S596034_I888892

On a T1-weighted brain MRI of a 47-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on supplementary motor cortex - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the amygdala - mild atrophy of the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0236_MR_t1_mprage__br_raw_20170628111617082_77_S576049_I865317

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: supramarginal gyrus (mild) - mild focal atrophy of frontal lobe on anterior orbital gyrus - mild focal atrophy of limbic cortex on middle cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the accumbens - no evidence of atrophy in the thalamus - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

NIFD_1_S_0275_MR_t1_mprage__br_raw_20170628134416812_120_S576437_I865788

On a T1-weighted brain MRI of a 66-year-old male subject, we observed the following: For the cerebral cortex: - moderate focal atrophy of frontal lobe on posterior orbital gyrus - mild focal atrophy of temporal lobe on inf. temporal gyrus - mild focal atrophy of parietal lobe on postcentral gyrus medial segment - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the caudate - no evidence of atrophy in the ventral dc - no evidence of atrophy in the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0296_MR_t1_mprage__br_raw_20160903221807406_7_S496904_I773244

On a T1-weighted brain MRI of a 65-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of parietal lobe on angular gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_1_S_0311_MR_T1_mprage_S3_DIS3D_br_raw_20160909141022230_61_S498005_I774570

On a T1-weighted brain MRI of a 75-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: postcentral gyrus (mild) - mild focal atrophy of frontal lobe on medial frontal cortex - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the putamen - mild bilateral atrophy of the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - moderate enlargement of the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

NIFD_2_S_0018_MR_MT1__GradWarp__N3m_Br_20120820135438042_S151967_I324982

On a T1-weighted brain MRI of a 64-year-old female subject, we observed the following: For the cerebral cortex: - moderate focal atrophy of frontal lobe on lateral orbital gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_009_S_4612_MR_MPRAGE_br_raw_20120329134729641_17_S145159_I294222

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of frontal lobe on medial orbital gyrus (mild) and subcallosal area (mild) - mild focal atrophy of limbic cortex on middle cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the putamen - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_136_S_4993_MR_MPRAGE_br_raw_20121025150812723_51_S172271_I342522

On a T1-weighted brain MRI of a 72-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on gyrus rectus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the inf. lateral ventricle, more pronounced on the left - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_100_S_5246_MR_MPRAGE_br_raw_20130823142052575_107_S199007_I387095

On a T1-weighted brain MRI of a 66-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the insular cortex, with focal volume reduction observed in the following subregions: central operculum (mild), anterior insula (mild) and parietal operculum (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: entorhinal area (mild) - atrophies of frontal lobe on triangular inf. frontal gyrus (mild) and sup. frontal gyrus (mild) - atrophies of temporal lobe on middle temporal gyrus (moderate), transverse temporal gyrus (moderate) and planum temporale (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - mild atrophy of the amygdala, more pronounced on the right - mild atrophy of the hippocampus, more pronounced on the right - mild bilateral atrophy of the ventral dc - no evidence of atrophy in the putamen - mild left atrophy of the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum For the ventricles: - mild enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - severe enlargement of the external csf - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

CN

ADNI_135_S_4954_MR_MPRAGE_br_raw_20120924115236764_47_S168533_I336502

On a T1-weighted brain MRI of a 62-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on posterior orbital gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the putamen - mild bilateral atrophy of the thalamus - mild left atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_068_S_4174_MR_MPRAGE_br_raw_20110822091529981_79_S119822_I251996

On a T1-weighted brain MRI of a 74-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on sup. frontal gyrus medial segment - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_099_S_4104_MR_MPRAGE_br_raw_20110701121555888_20_S113393_I243001

On a T1-weighted brain MRI of a 73-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of occipital lobe on middle occipital gyrus - mild focal atrophy of insular cortex on central operculum - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - mild enlargement of the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

ADNI_016_S_4583_MR_Accelerated_SAG_IR-SPGR__br_raw_20120329134055367_164_S145153_I294212

On a T1-weighted brain MRI of a 87-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the parietal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: precuneus (moderate) and supramarginal gyrus (mild) - mild atrophy of the temporal lobe, with focal volume reduction observed in the following subregions: inf. temporal gyrus (severe), transverse temporal gyrus (mild) and temporal pole (mild) - mild atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (mild) - atrophies of frontal lobe on sup. frontal gyrus medial segment (moderate) and precentral gyrus medial segment (mild) - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - mild atrophy of the amygdala, more pronounced on the right - mild right atrophy of the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_018_S_5240_MR_MPRAGE_br_raw_20130723160412209_118_S196225_I382181

On a T1-weighted brain MRI of a 63-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of insular cortex on frontal operculum - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_116_S_4483_MR_MPRAGE_br_raw_20120125125758694_69_S138478_I280672

On a T1-weighted brain MRI of a 70-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: parahippocampal gyrus (mild) - moderate focal atrophy of frontal lobe on sup. frontal gyrus - mild focal atrophy of temporal lobe on planum polare - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_003_S_4872_MR_Accelerated_SAG_IR-SPGR__br_raw_20120802165821857_15_S159410_I321379

On a T1-weighted brain MRI of a 69-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the basal forebrain - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_012_S_4642_MR_MPRAGE_br_raw_20120411102800059_1_S146874_I296878

On a T1-weighted brain MRI of a 59-year-old female subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_037_S_4770_MR_MPRAGE_br_raw_20120709115645978_143_S156967_I315489

On a T1-weighted brain MRI of a 76-year-old male subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: parahippocampal gyrus (mild) and middle cingulate gyrus (mild) - mild atrophy of the insular cortex, with focal volume reduction observed in the following subregions: anterior insula (mild) - atrophies of frontal lobe on gyrus rectus (moderate), middle frontal gyrus (mild), posterior orbital gyrus (mild) and subcallosal area (mild) - mild focal atrophy of temporal lobe on planum temporale - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the amygdala - moderate bilateral atrophy of the accumbens - mild atrophy of the hippocampus - mild left atrophy of the thalamus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_033_S_4179_MR_MPRAGE_br_raw_20110824115448295_113_S119874_I252069

On a T1-weighted brain MRI of a 83-year-old male subject, we observed the following: For the cerebral cortex: - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the thalamus - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_135_S_4566_MR_MPRAGE_br_raw_20120307141649080_11_S143148_I288820

On a T1-weighted brain MRI of a 84-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on frontal pole - atrophies of temporal lobe on middle temporal gyrus (mild) and planum temporale (mild) - mild focal atrophy of parietal lobe on angular gyrus - mild focal atrophy of insular cortex on posterior insula - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - no evidence of atrophy in the thalamus - no evidence of atrophy in the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

ADNI_003_S_4892_MR_Accelerated_SAG_IR-SPGR__br_raw_20120827170017619_71_S162721_I326457

On a T1-weighted brain MRI of a 75-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of parietal lobe on angular gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - moderate right atrophy of the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc - no evidence of atrophy in the amygdala - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_082_S_4090_MR_MPRAGE_br_raw_20110621154128802_119_S112177_I241094

On a T1-weighted brain MRI of a 72-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on anterior orbital gyrus - mild focal atrophy of parietal lobe on supramarginal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

CN

ADNI_009_S_5224_MR_MPRAGE_br_raw_20130717152112089_161_S195460_I381184

On a T1-weighted brain MRI of a 79-year-old male subject, we observed the following: For the cerebral cortex: - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: entorhinal area (moderate) and parahippocampal gyrus (mild) - mild atrophy of the insular cortex, more pronounced on the right - atrophies of temporal lobe on temporal pole (moderate) and middle temporal gyrus (mild) - mild focal atrophy of occipital lobe on inf. occipital gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the right - mild bilateral atrophy of the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild right enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_135_S_4657_MR_MPRAGE_br_raw_20120412141545566_116_S147060_I297169

On a T1-weighted brain MRI of a 72-year-old female subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, with focal volume reduction observed in the following subregions: middle temporal gyrus (severe), inf. temporal gyrus (moderate), temporal pole (moderate) and fusiform gyrus (mild) - moderate bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: angular gyrus (mild) - mild focal atrophy of occipital lobe on middle occipital gyrus - mild focal atrophy of limbic cortex on entorhinal area - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the amygdala - moderate bilateral atrophy of the hippocampus - no evidence of atrophy in the ventral dc - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_136_S_4433_MR_MPRAGE_br_raw_20120117163140145_52_S136879_I278511

On a T1-weighted brain MRI of a 77-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on triangular inf. frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_011_S_4906_MR_MPRAGE_br_raw_20120904143307512_81_S165942_I330056

On a T1-weighted brain MRI of a 76-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on sup. temporal gyrus - mild focal atrophy of parietal lobe on angular gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild atrophy of the hippocampus, more pronounced on the left - no evidence of atrophy in the thalamus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the ventral dc For the ventricles: - moderate left enlargement of the inf. lateral ventricle - mild left enlargement of the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_003_S_4840_MR_Accelerated_SAG_IR-SPGR__br_raw_20120729225426564_189_S158773_I319424

On a T1-weighted brain MRI of a 62-year-old female subject, we observed the following: For the cerebral cortex: - mild atrophy of the parietal lobe - mild focal atrophy of temporal lobe on transverse temporal gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_128_S_4586_MR_MPRAGE_br_raw_20120606093312228_102_S152929_I308307

On a T1-weighted brain MRI of a 77-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of parietal lobe on precuneus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the ventral dc - mild atrophy of the pallidum - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_094_S_4460_MR_Accelerated_SAG_IR-SPGR__br_raw_20120209083837573_192_S140247_I283576

On a T1-weighted brain MRI of a 67-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on middle frontal gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - mild right atrophy of the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_941_S_4376_MR_MPRAGE_br_raw_20120109153615951_58_S135785_I276860

On a T1-weighted brain MRI of a 77-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on middle frontal gyrus - moderate focal atrophy of parietal lobe on postcentral gyrus - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - mild left atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_012_S_4643_MR_MPRAGE_br_raw_20120416152536718_1_S147338_I297693

On a T1-weighted brain MRI of a 66-year-old female subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on planum polare - mild focal atrophy of occipital lobe on sup. occipital gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_021_S_4718_MR_Accelerated_Sag_IR-SPGR__br_raw_20120516162344538_10_S150673_I304759

On a T1-weighted brain MRI of a 79-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the parietal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: angular gyrus (moderate), postcentral gyrus (mild) and precuneus (mild) - mild atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: middle temporal gyrus (moderate), fusiform gyrus (mild) and inf. temporal gyrus (mild) - mild focal atrophy of frontal lobe on medial frontal cortex - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the amygdala - mild atrophy of the accumbens - mild right atrophy of the hippocampus - mild right atrophy of the thalamus - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle, more pronounced on the right - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_019_S_4477_MR_MPRAGE_br_raw_20120126085251352_103_S138533_I280783

On a T1-weighted brain MRI of a 83-year-old female subject, we observed the following: For the cerebral cortex: - mild bilateral atrophy of the parietal lobe - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (mild) - atrophies of frontal lobe on medial frontal cortex (mild) and opercular inf. frontal gyrus (mild) - mild focal atrophy of temporal lobe on middle temporal gyrus - mild focal atrophy of occipital lobe on occipital fusiform gyrus - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate bilateral atrophy of the accumbens, more pronounced on the right - moderate bilateral atrophy of the hippocampus - mild bilateral atrophy of the amygdala - no evidence of atrophy in the ventral dc - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - mild enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

AD

ADNI_052_S_5062_MR_Accelerated_Sag_IR-FSPGR_br_raw_20130128154823597_111_S181117_I356514

On a T1-weighted brain MRI of a 71-year-old female subject, we observed the following: For the cerebral cortex: - atrophies of temporal lobe on sup. temporal gyrus (moderate) and planum temporale (mild) - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild left atrophy of the amygdala - no evidence of atrophy in the accumbens - no evidence of atrophy in the putamen - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild left enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_067_S_4728_MR_MPRAGE_br_raw_20120601105317930_38_S152456_I307594

On a T1-weighted brain MRI of a 82-year-old male subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the temporal lobe, more pronounced on the right, with focal volume reduction observed in the following subregions: inf. temporal gyrus (moderate), temporal pole (moderate) and fusiform gyrus (mild) - atrophies of frontal lobe on gyrus rectus (mild), medial frontal cortex (mild) and middle frontal gyrus (mild) - mild focal atrophy of parietal lobe on sup. parietal lobule - mild focal atrophy of insular cortex on parietal operculum - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex For the subcortical structures: - moderate bilateral atrophy of the accumbens - moderate atrophy of the amygdala, more pronounced on the right - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - moderate enlargement of the inf. lateral ventricle, more pronounced on the right - mild bilateral enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_032_S_4304_MR_MPRAGE_br_raw_20111027142608296_157_S126598_I262773

On a T1-weighted brain MRI of a 76-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on anterior orbital gyrus - atrophies of temporal lobe on middle temporal gyrus (moderate) and temporal pole (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the limbic cortex - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild enlargement of the lateral ventricle - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

ADNI_036_S_4820_MR_MPRAGE_br_raw_20120718104734388_6_S157909_I316737

On a T1-weighted brain MRI of a 86-year-old female subject, we observed the following: For the cerebral cortex: - moderate bilateral atrophy of the occipital lobe, with focal volume reduction observed in the following subregions: inf. occipital gyrus (mild) - mild focal atrophy of temporal lobe on inf. temporal gyrus - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - mild bilateral atrophy of the accumbens - mild left atrophy of the hippocampus - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

AD

ADNI_014_S_4615_MR_MPRAGE_br_raw_20120330084522944_163_S145232_I294334

On a T1-weighted brain MRI of a 87-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of temporal lobe on temporal pole - mild focal atrophy of limbic cortex on anterior cingulate gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - moderate atrophy of the amygdala, more pronounced on the left - mild atrophy of the hippocampus, more pronounced on the left - mild left atrophy of the basal forebrain - no evidence of atrophy in the accumbens - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - mild left enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the external csf

AD

ADNI_019_S_4835_MR_MPRAGE_br_raw_20120711140807158_62_S157253_I315857

On a T1-weighted brain MRI of a 80-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of limbic cortex on posterior cingulate gyrus - no evidence of atrophy in the frontal lobe - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen - no evidence of atrophy in the thalamus For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

CN

NIFD_2_S_0029_MR_MT1__GradWarp__N3m_Br_20130103113440420_S178016_I353168

On a T1-weighted brain MRI of a 66-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the frontal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: gyrus rectus (severe), medial frontal cortex (severe), posterior orbital gyrus (severe), opercular inf. frontal gyrus (severe), middle frontal gyrus (severe), medial orbital gyrus (severe), sup. frontal gyrus medial segment (severe), lateral orbital gyrus (moderate), subcallosal area (moderate), frontal pole (mild), orbital inf. frontal gyrus (moderate), anterior orbital gyrus (moderate), precentral gyrus medial segment (mild) and sup. frontal gyrus (mild) - moderate atrophy of the limbic cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior cingulate gyrus (severe) and entorhinal area (mild) - moderate atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior insula (severe) and frontal operculum (mild) - mild atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (moderate) and middle temporal gyrus (mild) - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe For the subcortical structures: - severe bilateral atrophy of the accumbens, more pronounced on the left - severe bilateral atrophy of the caudate, more pronounced on the left - severe bilateral atrophy of the amygdala, more pronounced on the left - mild atrophy of the putamen, more pronounced on the left - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc - no evidence of atrophy in the hippocampus - no evidence of atrophy in the thalamus - no evidence of atrophy in the pallidum For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle, more pronounced on the left - severe bilateral enlargement of the lateral ventricle - moderate enlargement of the external csf - mild enlargement of the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD

NIFD_1_S_0005_MR_t1_mprage_S3_DIS3D_br_raw_20110414104256833_155_S104277_I227703

On a T1-weighted brain MRI of a 59-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on anterior orbital gyrus - mild focal atrophy of temporal lobe on planum polare - mild focal atrophy of limbic cortex on entorhinal area - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the caudate - moderate bilateral atrophy of the pallidum - moderate bilateral atrophy of the putamen - moderate bilateral atrophy of the thalamus - mild bilateral atrophy of the accumbens - no evidence of atrophy in the hippocampus - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0338_MR_T1_mprage_S3_DIS3D_br_raw_20170628235405397_61_S577729_I867439

On a T1-weighted brain MRI of a 59-year-old female subject, we observed the following: For the cerebral cortex: - severe atrophy of the temporal lobe, more pronounced on the left, with focal volume reduction observed in the following subregions: temporal pole (severe), inf. temporal gyrus (mild), middle temporal gyrus (mild) and fusiform gyrus (mild) - mild atrophy of the insular cortex, more pronounced on the left, with focal volume reduction observed in the following subregions: anterior insula (mild) - mild focal atrophy of frontal lobe on precentral gyrus medial segment - mild focal atrophy of occipital lobe on cuneus - mild focal atrophy of limbic cortex on entorhinal area - no evidence of atrophy in the parietal lobe For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - mild atrophy of the hippocampus, more pronounced on the left - mild left atrophy of the putamen - no evidence of atrophy in the caudate - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc - no evidence of atrophy in the accumbens - no evidence of atrophy in the basal forebrain For the ventricles: - severe enlargement of the inf. lateral ventricle, more pronounced on the left - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_2_S_0021_MR_MT1__GradWarp__N3m_Br_20130114173911629_S160243_I355049

On a T1-weighted brain MRI of a 60-year-old male subject, we observed the following: For the cerebral cortex: - mild focal atrophy of frontal lobe on opercular inf. frontal gyrus - mild focal atrophy of limbic cortex on middle cingulate gyrus - no evidence of atrophy in the temporal lobe - no evidence of atrophy in the parietal lobe - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - no evidence of atrophy in the putamen - no evidence of atrophy in the accumbens - no evidence of atrophy in the amygdala - no evidence of atrophy in the basal forebrain - no evidence of atrophy in the caudate - no evidence of atrophy in the hippocampus - no evidence of atrophy in the pallidum - no evidence of atrophy in the thalamus - no evidence of atrophy in the ventral dc For the ventricles: - no evidence of enlargements in the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle - no evidence of enlargements in the external csf

FTD

NIFD_1_S_0018_MR_t1_mprage__br_raw_20170814165807711_159_S594325_I886781

On a T1-weighted brain MRI of a 71-year-old male subject, we observed the following: For the cerebral cortex: - severe bilateral atrophy of the temporal lobe, with focal volume reduction observed in the following subregions: inf. temporal gyrus (severe), temporal pole (severe) and middle temporal gyrus (moderate) - mild bilateral atrophy of the parietal lobe, with focal volume reduction observed in the following subregions: sup. parietal lobule (mild) - mild atrophy of the limbic cortex, with focal volume reduction observed in the following subregions: entorhinal area (mild) and anterior cingulate gyrus (mild) - mild focal atrophy of frontal lobe on subcallosal area - no evidence of atrophy in the occipital lobe - no evidence of atrophy in the insular cortex For the subcortical structures: - severe bilateral atrophy of the amygdala, more pronounced on the left - moderate bilateral atrophy of the accumbens, more pronounced on the right - moderate bilateral atrophy of the hippocampus - mild atrophy of the thalamus, more pronounced on the right - no evidence of atrophy in the basal forebrain - mild left atrophy of the caudate - no evidence of atrophy in the ventral dc - no evidence of atrophy in the pallidum - no evidence of atrophy in the putamen For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no evidence of enlargements in the lateral ventricle - severe enlargement of the external csf - no evidence of enlargements in the 3rd ventricle - no evidence of enlargements in the 4th ventricle

FTD